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(extracted
from ZhongKe printed materials)
As a medicinal nutrient, the ganoderma has a very long history.
More than 3000 years ago, our ancestors began to use it to cure
diseases and it was praised as the "Oriental Miracle Herb"
for its remarkable effect. It is a household legend that ganoderma
is able to "brings the dead back to life". Ganoderma
spore is the essence of ganoderma and only one gram of ganoderma
spore can be derived from 1000 grams of ganoderma.
Functional
Mechanism
Ganoderma spore is a combination of triterpene, polysaccharides,
polypeptide, glucopeptide, adenosine, enzyme, alkoloid, organic
germanium and multiple trace elements and thus it is endowed
with strong physiological activity, suitable for independent
application or integrated application.
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Tumor
Restriction Mechanism
By stimulating the body-intrinsic effector cell* with cytotoxicity,
ganoderma spore promotes the biological activity of retothelium
and kills the tumor cells, restricting the growth of tumor or
eliminating tumor.
1. Activates effector cells of body, enhances the ability of body
to kill tumor and of oncolysis, raises the activity of damaging
the tumor for over 80%.
2. Induce the secretion and synthesis of cells factor, enhances
the ability of body to kill tumor, activates effector cells, and
protects normal cells.
3. Restrains immune suppressor factor produced by tumor cells,
exposes tumor cells to killer cells.
4. Restrains tumor cells from growing.
5. Repairs and enhances the sensibility of body to cancer effector,
enhances adaptability of body.
6. Eliminates radicals so as to show strong activity of superoxide
dismutase in body.
7. Improves the synthesis of marrow cells DNA, RNA and protein,
accelerates splitting and propagation of marrow cells, and enhances
blood producing function of marrow.
8. Reduces surface potential of cancer cells, inducts cancer cells
gene to mutate again and initiate its fading program.
9. Kills tumor cells, but its mechanism remains unknown so far.
Zooperal result shows that Ganoderma Spore has the inhibitive
function to transplantable tumors.
Sarcoma 180: 86.9 ~ 91.0% Leukemia P388:
66.5 ~78.4%
Liver Cancer AH-13, AH-7974, AH-66F: 65.1~71%
Rous Cancer : 81.5 ~ 89.6% Malign Fibroma : 86.0 ~ 98.0%
EC Ehrilich Carcinoma : 79.3 ~ 87.6% Ascitic HEPS Liver Cancer
: 44.7 ~ 56.0%
*Effector Cell : T Cell, macrophage (MF), natural killer (NK)
and lymph-cell activated killer (LAK).
**Cell Factor: interferon (IFN), interleukin (IL), tumor necrosis
factor (TNF) and clone stimulus factor (CSF).
Toxicology
1. Acute Toxicity Experiment : LD50 for both female and male mice
is over 21.5g/kg.
2. Ames Experiment : Standard test bacteria TA97a. TA98, TA100
and TA102, flat oozing process, dosage 5000ug/one, with adding
S-9 or not, which shows no obvious sign of induction activity.
3. Polychromatophilic normacyte micronucleus test on mice bone
marrow : Dosage is up to 10g/kg (weight) and no induction activity
of the male and female mice has been detected on polychromatophilic
normocyte of bone marrow.
4. Induction activity of primary spermatocyte chromosome of mice
spermary.
5. Dosage is up to 10g/kg (weight) and no induction activity has
been detected on primary spermatocyte chromo some of male mice
spermary.
Auxiliary
application to cancer inhibition
1. Promote the curing effect. Cancer-inhibitive effect can be
increased when used with radiation therapy and chemotherapy. For
63.2 ~ 71.5% of all the cases, the therapeutic effect is enhanced
(for 23%, the therapeutic period is shortened) and for 24.5 ~
33.9%, the effect of radiation therapy is enhanced.
2. Create therapeutic opportunity: for cases that therapeutic
indication is restored for dying patients and patents receiving
the conservative treatment, of which, 11.3 ~ 20.9% can resume
radiation therapy and chemotherapy. This product can help post-operational
cut to heal rapidly and recover physically so as to receive radiation
therapy and chemotherapy as soon as possible.
3. Prevents tumor from rapid diffusion.
4. Reduces side effect: the toxic effect has been reduced to low
during radiation therapy and chemotherapy and the bone marrow
is eased. For 80.6 ~ 87.0% of the cases, the white cell is kept
within the limit; for 55.8 ~64.2% of the patients, no vomiting
and the rest can stop vomiting within 1 ~ 3 days; for 17.5 ~ 23%,
they suffer from slight lapsus pilorum; Over 95% with normal sleep
and diet.
5. Improve life Quality: during the whole lapse, the life quality
is considerably improved. Increased diet : 100%; Better sleep:
100%; restored vitality : 100%; restored white cell : 90%; relieved
from pain : 70%; improve oppilate : 60%; bedridden patients can
walk about now : 65%
6. Prolonged Survival: 100% of patients who took in various dosages
can outlive the estimated survival.
Decrement
of White Blood Cell
Ganoderma Spore can enhance the synthesis of the marrow cell protein
and nucleid acid, speed up the separation and proliferation of
marrow cells and relieve the marrow inhibition. It is effective
to the white blood cell decrement incurred during the process
of radiation therapy, chemotherapy and other reasons and the efficiency
of therapy is 84.6%.
Chronic
Bronchitis and Asthma
Ganoderma Spore can enhance the reproduction of cilium epicyte
of the trachea and the repair of the cartilage deformation of
he trachea and restrain the release of amine and the rivalry acetylcholine
to relieve the spasm of the smooth muscle. It is effective to
the cough, sputun and asthma typical of bronchitis and the efficiency
to asthma is 80%.
Diabetics
Spore can increase the concentration of plasma insulin and speed
up the metabolism of glucose. It not only enhances the utility
of saccharine by surrounding tissues but also strengthens the
activity of the crucial enzyme through the metabolism of saccharine
in the liver to promote the utility rate of saccharine by the
liver. For example, it can promote the activity of glucose kinase
and glucose-6-phosphate dehydrogenase to decrease the activity
of the synthetase.
Hypertension
and Hyperlipemia
Shell broken Ganoderma Spore can restrain the activity of antiotensin
enzyme and the efficiency is 87%. It can obviously reduce the
concentration of cholesterol, triglyceride and ß-fatty protein
to reduce blood fat and prevent hepar adiposum.
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